Generic Solosec
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Active component:
SecnidazolePackages: 1 g |
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In mid-September, the FDA registered a new drug for the treatment of non – pregnant women with bacterial vaginosis-Secnidazole (Solosec™) produced by Symbiomix Therapeutics.
Actually, the drug is not new, because the first time it was mentioned in PubMed was in 1976. But since then, it has not entered the US market. It seems to me that he is of French origin.
Secnidazole is a drug of the 5-nitroimidazole group with activity against many gram-negative anaerobes, as well as gram-positive bacteria. At the same time, it "does not touch" the beneficial bacteria of the genus Lactobacillus, which protect the vaginal mucosa from infections.
The drug also has improved pharmacokinetic characteristics: its half-life is 17 hours compared to 8 hours for metronidazole. This allows you to use a single-dose regimen, which is equivalent in effectiveness to a 5-7-day course of metronidazole.
Actually, the drug is not new, because the first time it was mentioned in PubMed was in 1976. But since then, it has not entered the US market. It seems to me that he is of French origin.
Secnidazole is a drug of the 5-nitroimidazole group with activity against many gram-negative anaerobes, as well as gram-positive bacteria. At the same time, it "does not touch" the beneficial bacteria of the genus Lactobacillus, which protect the vaginal mucosa from infections.
The drug also has improved pharmacokinetic characteristics: its half-life is 17 hours compared to 8 hours for metronidazole. This allows you to use a single-dose regimen, which is equivalent in effectiveness to a 5-7-day course of metronidazole.